In
Civilized Man’s Eight Deadly Sins, Nobel Prize winner
Konrad Lorenz, wrote about the pursuit of happiness:
Pleasure may be achieved without paying the price of strenuous effort, but joy cannot. Intolerance of unpleasurable experience converts the natural ups and downs of human life into an artificial plain, the great waves of mountain and valley becoming a scarcely noticeable ripple, and light and shade a monotonous gray. In short, intolerance of unpleasurable experience creates deadly boredom.
The wish to avoid all suffering implies the withdrawal from an essential part of human life.